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Event Details

Who is this event intended for? Anyone involved or interested in learning more about trial design.

What is the benefit of attending? Learn about the current hot topics in adaptive designs and gain insight on how to use them in practice.


Adaptive designs can offer more efficient trials for answering many questions of scientific interests. In this event we explore both cutting edge methodology for both the design and analysis of such designs. The speakers will offer insight into the use of such methods in the pharmaceutical setting, sharing their experiences from designing such trials. We will also hear opinions on the upcoming ICH E20 guidance. This event will be run in a hybrid format. We hope you will be able to join us in Cambridge and benefit from the opportunity to speak with others working in this area. For those that cannot attend there will be the option to attend online in the online one day meeting format that has been more familiar in recent times.

Oct 13, 2022

10:00 AM - 4:00 PMGMT+1

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MRC Biostatistics Unit
University of Cambridge
East Forvie Building
Forvie Site
Robinson Way
Cambridge Biomedical Campus

Cambridge, United Kingdom

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PSI Member (Face-to-Face attendance)
Member Price £40
PSI Non-Member (Face-to-Face attendance)


  • 10:00 AM - 10:05 AMWelcome
    10:05 AM - 10:40 AMSofia Villar:- Response Adaptive Randomisation
    10:40 AM - 11:15 AMFrank Bretz and Uli Burger:- Our personal views on adaptive designs
    11:15 AM - 11:30 AMCoffee Break
    11:30 AM - 12:05 PMCarl-Fredrik Burman:- Adaptive Designs with Multiple Objectives
    12:05 PM - 12:40 PMAnh Nguyen:- Adaptive Enrichment Design to Address Emerging Uncertainty Regarding Optimal Target Population
    12:40 PM - 1:30 PMLunch Break
    1:30 PM - 2:05 PMHaiyan Zheng:- Design and analysis of basket trials to enable added efficiency
    2:05 PM - 2:40 PMOlivier Collignon:- Estimands and Complex Innovative Designs
    2:40 PM - 2:55 PMCoffee Break
    2:55 PM - 3:30 PMPantelis Vlachos:- Simulation-based optimization of adaptive designs
    3:30 PM - 3:55 PMPanel Discussion
    3:55 PM - 4:00 PMClosing Remarks


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